Severe Hepatic Failure Related to Nevirapine Treatment

Severe hepatic failure related to nevirapine treatment.

markable. Laboratory evaluations were significant for a leukocyte count of 1,500/mm (normal value, 4,500–11,000/mm) and macrocytic anemia (hematocrit, 30%; hemoglobin level, 9.8 g/dL; mean corpuscular volume, 104.6 fL). The absolute neutrophil and lymphocyte counts were 870 and 600/mm, respectively. The blood urea nitrogen level was 34 mg/dL (normal value, 7–22 mg/dL), and the creatinine level ...

hepatic failure related to itraconazole use successfully treated by corticosteroids

Fulminant hepatic failure due to metastatic choroidal melanoma

Low-frequency nevirapine resistance at multiple sites may predict treatment failure in infants on nevirapine-based treatment.

BACKGROUND Resistance commonly arises in infants exposed to single-dose nevirapine (sdNVP) for prevention of mother to child transmission. Although K103N and Y181C are common following sdNVP, multiple other mutations also confer NVP resistance. It remains unclear whether specific NVP resistance mutations or combinations of mutations predict virologic failure in infants when present at low frequ...

Folliculotropic mycosis fungoides with severe hepatic failure due to hepatic involvement.

© 2009 The Authors. doi: 10.2340/00015555-0665 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Folliculotropic mycosis fungoides (MF) is a rare variant of MF characterized by the presence of folliculotropic infiltrates and preferential involvement of the head and neck area. The prognosis of patients with folliculotropic MF is worse than that of patients with classical...